Pre-hypertrophic chondrogenic enhancer landscape of limb and axial skeleton development
Pre-hypertrophic chondrogenic enhancer landscape of limb and axial skeleton development
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Chondrocyte differentiation controls skeleton development and stature. Here we provide a comprehensive map of chondrocyte-specific enhancers and show that they provide a mechanistic framework through which non-coding genetic variants can influence skeletal development and human stature. Working with fetal chondrocytes isolated from mice bearing a
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Full title
Pre-hypertrophic chondrogenic enhancer landscape of limb and axial skeleton development
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TN_cdi_doaj_primary_oai_doaj_org_article_b064cf129fd146118f68faab2889d660
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b064cf129fd146118f68faab2889d660
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-49203-2
