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Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasio...

Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b0719b6765a344b9be1d3cda2cef7538

Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion

About this item

Full title

Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-06, Vol.10 (1), p.2666-12, Article 2666

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Ran is a nucleocytoplasmic shuttle protein that is involved in cell cycle regulation, nuclear-cytoplasmic transport, and cell transformation. Ran plays an important role in cancer cell survival and cancer progression. Here, we show that, in addition to the nucleocytoplasmic localization of Ran, this GTPase is specifically associated with the plasma...

Alternative Titles

Full title

Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b0719b6765a344b9be1d3cda2cef7538

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b0719b6765a344b9be1d3cda2cef7538

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-10570-w

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