Identification of allele-specific KIV-2 repeats and impact on Lp(a) measurements for cardiovascular...
Identification of allele-specific KIV-2 repeats and impact on Lp(a) measurements for cardiovascular disease risk
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Full title
Author / Creator
Behera, Sairam , Belyeu, Jonathan R. , Chen, Xiao , Paulin, Luis F. , Nguyen, Ngoc Quynh H. , Newman, Emma , Mahmoud, Medhat , Menon, Vipin K. , Qi, Qibin , Joshi, Parag , Marcovina, Santica , Rossi, Massimiliano , Roller, Eric , Han, James , Onuchic, Vitor , Avery, Christy L. , Ballantyne, Christie M. , Rodriguez, Carlos J. , Kaplan, Robert C. , Muzny, Donna M. , Metcalf, Ginger A. , Gibbs, Richard A. , Yu, Bing , Boerwinkle, Eric , Eberle, Michael A. and Sedlazeck, Fritz J.
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
The abundance of Lp(a) protein holds significant implications for the risk of cardiovascular disease (CVD), which is directly impacted by the copy number (CN) of KIV-2, a 5.5 kbp sub-region. KIV-2 is highly polymorphic in the population and accurate analysis is challenging. In this study, we present the DRAGEN KIV-2 CN caller, which utilizes short...
Alternative Titles
Full title
Identification of allele-specific KIV-2 repeats and impact on Lp(a) measurements for cardiovascular disease risk
Authors, Artists and Contributors
Author / Creator
Belyeu, Jonathan R.
Chen, Xiao
Paulin, Luis F.
Nguyen, Ngoc Quynh H.
Newman, Emma
Mahmoud, Medhat
Menon, Vipin K.
Qi, Qibin
Joshi, Parag
Marcovina, Santica
Rossi, Massimiliano
Roller, Eric
Han, James
Onuchic, Vitor
Avery, Christy L.
Ballantyne, Christie M.
Rodriguez, Carlos J.
Kaplan, Robert C.
Muzny, Donna M.
Metcalf, Ginger A.
Gibbs, Richard A.
Yu, Bing
Boerwinkle, Eric
Eberle, Michael A.
Sedlazeck, Fritz J.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b08e11c0c6a64b4e840870232441e2bd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b08e11c0c6a64b4e840870232441e2bd
Other Identifiers
ISSN
1755-8794
E-ISSN
1755-8794
DOI
10.1186/s12920-024-02024-0
