Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica
Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Aquaporin-4-immunoglobulin G (AQP4-IgG) seropositive neuromyelitis optica spectrum disorder (herein called NMO) is an autoimmune disease of the central nervous system in which AQP4-IgG binding to AQP4 on astrocytes results in complement-dependent astrocyte injury and secondary inflammation, demyelination, and neuron loss. We previously reported evi...
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Full title
Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica
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TN_cdi_doaj_primary_oai_doaj_org_article_b09273c1d1044c119b293fb3f0c8f50a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b09273c1d1044c119b293fb3f0c8f50a
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-018-1333-z
