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Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity an...

Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity an...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b09e032290ec4192805c9a19aa899151

Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity and cortical connectivity

About this item

Full title

Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity and cortical connectivity

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2023-05, Vol.133 (10), p.1-14

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Despite advances in acute care, ischemic stroke remains a major cause of long-term disability. Approaches targeting both neuronal and glial responses are needed to enhance recovery and improve long-term outcome. The complement C3a receptor (C3aR) is a regulator of inflammation with roles in neurodevelopment, neural plasticity, and neurodegeneration...

Alternative Titles

Full title

Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity and cortical connectivity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b09e032290ec4192805c9a19aa899151

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b09e032290ec4192805c9a19aa899151

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI162253

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