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Molecular mechanism for direct actin force-sensing by α-catenin

Molecular mechanism for direct actin force-sensing by α-catenin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b10232867b744f808e382a22565469d5

Molecular mechanism for direct actin force-sensing by α-catenin

About this item

Full title

Molecular mechanism for direct actin force-sensing by α-catenin

Publisher

England: eLife Sciences Publications, Ltd

Journal title

eLife, 2020-09, Vol.9

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications, Ltd

More information

Scope and Contents

Contents

The actin cytoskeleton mediates mechanical coupling between cells and their tissue microenvironments. The architecture and composition of actin networks are modulated by force; however, it is unclear how interactions between actin filaments (F-actin) and associated proteins are mechanically regulated. Here we employ both optical trapping and bioche...

Alternative Titles

Full title

Molecular mechanism for direct actin force-sensing by α-catenin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b10232867b744f808e382a22565469d5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b10232867b744f808e382a22565469d5

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.62514

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