Identification of LARS as an essential gene for osteosarcoma proliferation through large-Scale CRISP...
Identification of LARS as an essential gene for osteosarcoma proliferation through large-Scale CRISPR-Cas9 screening database and experimental verification
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Osteosarcoma is one of the most malignant tumors, and it occurs mostly in children and adolescents. Currently, surgery and chemotherapy are the main treatments. The recurrence rate is high and the prognosis is often poor. Finding an effective target gene therapy for osteosarcoma may effectively improve its prognosis.
In this study, genes essenti...
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Identification of LARS as an essential gene for osteosarcoma proliferation through large-Scale CRISPR-Cas9 screening database and experimental verification
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TN_cdi_doaj_primary_oai_doaj_org_article_b11054de898142da8c56bb3e7a167645
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b11054de898142da8c56bb3e7a167645
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ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-022-03571-9
