Maralixibat for the treatment of PFIC: Long‐term, IBAT inhibition in an open‐label, Phase 2 study
Maralixibat for the treatment of PFIC: Long‐term, IBAT inhibition in an open‐label, Phase 2 study
About this item
Full title
Author / Creator
Loomes, Kathleen M. , Squires, Robert H. , Kelly, Deirdre , Rajwal, Sanjay , Soufi, Nisreen , Lachaux, Alain , Jankowska, Irena , Mack, Cara , Setchell, Kenneth D. R. , Karthikeyan, Palaniswamy , Kennedy, Ciara , Dorenbaum, Alejandro , Desai, Nirav K. , Garner, Will , Jaecklin, Thomas , Vig, Pamela , Miethke, Alexander and Thompson, Richard J.
Publisher
United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
Journal title
Language
English
Formats
Publication information
Publisher
United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
Subjects
More information
Scope and Contents
Contents
Children with progressive familial intrahepatic cholestasis, including bile salt export pump (BSEP) and familial intrahepatic cholestasis–associated protein 1 (FIC1) deficiencies, suffer debilitating cholestatic pruritus that adversely affects growth and quality of life (QoL). Reliance on surgical interventions, including liver transplantation, hig...
Alternative Titles
Full title
Maralixibat for the treatment of PFIC: Long‐term, IBAT inhibition in an open‐label, Phase 2 study
Authors, Artists and Contributors
Author / Creator
Squires, Robert H.
Kelly, Deirdre
Rajwal, Sanjay
Soufi, Nisreen
Lachaux, Alain
Jankowska, Irena
Mack, Cara
Setchell, Kenneth D. R.
Karthikeyan, Palaniswamy
Kennedy, Ciara
Dorenbaum, Alejandro
Desai, Nirav K.
Garner, Will
Jaecklin, Thomas
Vig, Pamela
Miethke, Alexander
Thompson, Richard J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b1254fad7eda4d029fb251fe1e6c2b23
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b1254fad7eda4d029fb251fe1e6c2b23
Other Identifiers
ISSN
2471-254X
E-ISSN
2471-254X
DOI
10.1002/hep4.1980
