Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-ß1...
Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-ß1 secretion
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Author / Creator
Ren, Yu , Jia, Huan-Huan , Xu, Yi-Qi , Zhou, Xuan , Zhao, Xiao-Hui , Wang, Yun-Fei , Song, Xin , Zhu, Zhi-Yan , Sun, Ting , Dou, Yan , Tian, Wei-Ping , Zhao, Xiu-Lan , Kang, Chun-Sheng and Mei, Mei
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The communication between carcinoma associated fibroblasts (CAFs) and cancer cells facilitate tumor metastasis. In this study, we further underlying the epigenetic mechanisms of CAFs feed the cancer cells and the molecular mediators involved in these processes.
MCF-7 and MDA-MB-231 cells were treated with CAFs culture conditioned medium, respect...
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Full title
Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-ß1 secretion
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TN_cdi_doaj_primary_oai_doaj_org_article_b129b00aeff34d6ca3f3568bffb7054a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b129b00aeff34d6ca3f3568bffb7054a
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-018-0758-4