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A Systems Biology Approach to Understanding the Mechanisms of Action of an Alternative Anticancer Co...

A Systems Biology Approach to Understanding the Mechanisms of Action of an Alternative Anticancer Co...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b182f5a1d6ba4678b379498d1c20d156

A Systems Biology Approach to Understanding the Mechanisms of Action of an Alternative Anticancer Compound in Comparison to Cisplatin

About this item

Full title

A Systems Biology Approach to Understanding the Mechanisms of Action of an Alternative Anticancer Compound in Comparison to Cisplatin

Publisher

Switzerland: MDPI AG

Journal title

Proteomes, 2014-11, Vol.2 (4), p.501-526

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Many clinically available anticancer compounds are designed to target DNA. This commonality of action often yields overlapping cellular response mechanisms and can thus detract from drug efficacy. New compounds are required to overcome resistance mechanisms that effectively neutralise compounds like cisplatin and those with similar chemical structu...

Alternative Titles

Full title

A Systems Biology Approach to Understanding the Mechanisms of Action of an Alternative Anticancer Compound in Comparison to Cisplatin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b182f5a1d6ba4678b379498d1c20d156

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b182f5a1d6ba4678b379498d1c20d156

Other Identifiers

ISSN

2227-7382

E-ISSN

2227-7382

DOI

10.3390/proteomes2040501

How to access this item