Somatic Accumulation of GluA1-AMPA Receptors Leads to Selective Cognitive Impairments in Mice
Somatic Accumulation of GluA1-AMPA Receptors Leads to Selective Cognitive Impairments in Mice
About this item
Full title
Author / Creator
Publisher
Switzerland: Frontiers Research Foundation
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: Frontiers Research Foundation
Subjects
More information
Scope and Contents
Contents
The GluA1 subunit of the L-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) plays a crucial, but highly selective, role in cognitive function. Here we analyzed AMPAR expression, AMPAR distribution and spatial learning in mice (
), expressing the "trafficking compromised" GluA1(Q600R) point mutation. Our analysis revealed som...
Alternative Titles
Full title
Somatic Accumulation of GluA1-AMPA Receptors Leads to Selective Cognitive Impairments in Mice
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b1bc7d8f548849c9b8a8170e463b858f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b1bc7d8f548849c9b8a8170e463b858f
Other Identifiers
ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2018.00199
