Inhibition of the Neuronal Calcium Sensor DREAM Modulates Presenilin-2 Endoproteolysis
Inhibition of the Neuronal Calcium Sensor DREAM Modulates Presenilin-2 Endoproteolysis
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Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Deregulated intracellular Ca
and protein homeostasis underlie synaptic dysfunction and are common features in neurodegenerative diseases. DREAM, also known as calsenilin or KChIP-3, is a multifunctional Ca
binding protein of the neuronal calcium sensor superfamily with specific functions through protein-DNA and protein-protein interactions. S...
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Inhibition of the Neuronal Calcium Sensor DREAM Modulates Presenilin-2 Endoproteolysis
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TN_cdi_doaj_primary_oai_doaj_org_article_b1f3a54c4c664443b6790d2c4da87c75
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b1f3a54c4c664443b6790d2c4da87c75
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2018.00449
