Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast
Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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To obtain rates of mRNA synthesis and decay in yeast, we established dynamic transcriptome analysis (DTA). DTA combines non‐perturbing metabolic RNA labeling with dynamic kinetic modeling. DTA reveals that most mRNA synthesis rates are around several transcripts per cell and cell cycle, and most mRNA half‐lives range around a median of 11 min. DTA...
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Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast
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TN_cdi_doaj_primary_oai_doaj_org_article_b22de4ccc53e4bbea78faaba025fb0d6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b22de4ccc53e4bbea78faaba025fb0d6
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.1038/msb.2010.112
