Downregulation of XBP1 protects kidney against ischemia-reperfusion injury via suppressing HRD1-medi...
Downregulation of XBP1 protects kidney against ischemia-reperfusion injury via suppressing HRD1-mediated NRF2 ubiquitylation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Ischemia-reperfusion (IR) injury to the renal epithelia is associated with endoplasmic reticulum stress (ERS) and mitochondria dysfunction, which lead to oxidative stress-induced acute kidney injury (AKI). X-box binding protein 1 (XBP1), an ERS response protein, could play a prominent role in IR-induced AKI. In this study, we revealed that XBP1 and...
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Downregulation of XBP1 protects kidney against ischemia-reperfusion injury via suppressing HRD1-mediated NRF2 ubiquitylation
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TN_cdi_doaj_primary_oai_doaj_org_article_b22fe71ffe7e4f489f8a0cbc72d0ff0f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b22fe71ffe7e4f489f8a0cbc72d0ff0f
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ISSN
2058-7716
E-ISSN
2058-7716
DOI
10.1038/s41420-021-00425-z
