Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and ce...
Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity
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Publisher
England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Developmental trajectories of gene expression may reverse in their direction during ageing, a phenomenon previously linked to cellular identity loss. Our analysis of cerebral cortex, lung, liver, and muscle transcriptomes of 16 mice, covering development and ageing intervals, revealed widespread but tissue-specific ageing-associated expression reve...
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Full title
Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity
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TN_cdi_doaj_primary_oai_doaj_org_article_b23ed52f86bf4ad88499afb3416a1406
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b23ed52f86bf4ad88499afb3416a1406
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.68048
