PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts
PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts
About this item
Full title
Author / Creator
Amodio, Giuseppina , Moltedo, Ornella , Fasano, Dominga , Zerillo, Lucrezia , Oliveti, Marco , Di Pietro, Paola , Faraonio, Raffaella , Barone, Paolo , Pellecchia, Maria Teresa , De Rosa, Anna , De Michele, Giuseppe , Polishchuk, Elena , Polishchuk, Roman , Bonifati, Vincenzo , Nitsch, Lucio , Pierantoni, Giovanna Maria , Renna, Maurizio , Criscuolo, Chiara , Paladino, Simona and Remondelli, Paolo
Publisher
Switzerland: Frontiers Research Foundation
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: Frontiers Research Foundation
Subjects
More information
Scope and Contents
Contents
PARK20, an early onset autosomal recessive parkinsonism is due to mutations in the phosphatidylinositol-phosphatase Synaptojanin 1 (Synj1). We have recently shown that the early endosomal compartments are profoundly altered in PARK20 fibroblasts as well as the endosomal trafficking. Here, we report that PARK20 fibroblasts also display a drastic alt...
Alternative Titles
Full title
PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts
Authors, Artists and Contributors
Author / Creator
Moltedo, Ornella
Fasano, Dominga
Zerillo, Lucrezia
Oliveti, Marco
Di Pietro, Paola
Faraonio, Raffaella
Barone, Paolo
Pellecchia, Maria Teresa
De Rosa, Anna
De Michele, Giuseppe
Polishchuk, Elena
Polishchuk, Roman
Bonifati, Vincenzo
Nitsch, Lucio
Pierantoni, Giovanna Maria
Renna, Maurizio
Criscuolo, Chiara
Paladino, Simona
Remondelli, Paolo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b26864833e714333b88e97b9181fbe9e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b26864833e714333b88e97b9181fbe9e
Other Identifiers
ISSN
1662-4548
E-ISSN
1662-453X
DOI
10.3389/fnins.2019.00673
