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Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium fa...

Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium fa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b2750bae516e4b6997925ef758050641

Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum

About this item

Full title

Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum

Publisher

England: John Wiley & Sons, Inc

Journal title

MicrobiologyOpen (Weinheim), 2019-07, Vol.8 (7), p.e00779-n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

The appearance of multi‐drug resistant strains of malaria poses a major challenge to human health and validated drug targets are urgently required. To define a protein's function in vivo and thereby validate it as a drug target, highly specific tools are required that modify protein function with minimal cross‐reactivity. While modern genetic appro...

Alternative Titles

Full title

Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b2750bae516e4b6997925ef758050641

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b2750bae516e4b6997925ef758050641

Other Identifiers

ISSN

2045-8827

E-ISSN

2045-8827

DOI

10.1002/mbo3.779

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