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Proline, hydroxyproline, and pyrrolidone carboxylic acid derivatives as highly efficient but reversi...

Proline, hydroxyproline, and pyrrolidone carboxylic acid derivatives as highly efficient but reversi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b275d19b1b834e62862dd3f0d1eca52d

Proline, hydroxyproline, and pyrrolidone carboxylic acid derivatives as highly efficient but reversible transdermal permeation enhancers

About this item

Full title

Proline, hydroxyproline, and pyrrolidone carboxylic acid derivatives as highly efficient but reversible transdermal permeation enhancers

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-11, Vol.12 (1), p.19495-10, Article 19495

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Overcoming the skin barrier properties efficiently, temporarily, and safely for successful transdermal drug delivery remains a challenge. We synthesized three series of potential skin permeation enhancers derived from natural amino acid derivatives proline, 4-hydroxyproline, and pyrrolidone carboxylic acid, which is a component of natural moisturiz...

Alternative Titles

Full title

Proline, hydroxyproline, and pyrrolidone carboxylic acid derivatives as highly efficient but reversible transdermal permeation enhancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b275d19b1b834e62862dd3f0d1eca52d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b275d19b1b834e62862dd3f0d1eca52d

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-24108-6

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