Structural basis for lipid-mediated activation of G protein-coupled receptor GPR55
Structural basis for lipid-mediated activation of G protein-coupled receptor GPR55
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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GPR55 is an orphan G protein-coupled receptor (GPCR) and represents a promising drug target for cancer, inflammation, and metabolic diseases. The endogenous activation of lipid GPCRs can be solely mediated by membrane components and different lipids have been proposed as endogenous activators of GPR55, such as cannabinoids and lysophosphatidylinosi...
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Structural basis for lipid-mediated activation of G protein-coupled receptor GPR55
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TN_cdi_doaj_primary_oai_doaj_org_article_b29fd9c5c20d403585c4005f9a5d126d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b29fd9c5c20d403585c4005f9a5d126d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-57204-y
