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Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results...

Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b2cb84032e6c41d894a0979aff381d60

Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)

About this item

Full title

Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)

Publisher

England: BioMed Central Ltd

Journal title

Journal for immunotherapy of cancer, 2018-06, Vol.6 (1), p.63-63, Article 63

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The Tumor Inflammation Signature (TIS) is an investigational use only (IUO) 18-gene signature that measures a pre-existing but suppressed adaptive immune response within tumors. The TIS has been shown to enrich for patients who respond to the anti-PD1 agent pembrolizumab. To explore this immune phenotype within and across tumor types, we applied th...

Alternative Titles

Full title

Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b2cb84032e6c41d894a0979aff381d60

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b2cb84032e6c41d894a0979aff381d60

Other Identifiers

ISSN

2051-1426

E-ISSN

2051-1426

DOI

10.1186/s40425-018-0367-1

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