Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results...
Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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The Tumor Inflammation Signature (TIS) is an investigational use only (IUO) 18-gene signature that measures a pre-existing but suppressed adaptive immune response within tumors. The TIS has been shown to enrich for patients who respond to the anti-PD1 agent pembrolizumab. To explore this immune phenotype within and across tumor types, we applied th...
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Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)
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TN_cdi_doaj_primary_oai_doaj_org_article_b2cb84032e6c41d894a0979aff381d60
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b2cb84032e6c41d894a0979aff381d60
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ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1186/s40425-018-0367-1