Inhibition of mTOR signaling protects human glioma cells from hypoxia-induced cell death in an autop...
Inhibition of mTOR signaling protects human glioma cells from hypoxia-induced cell death in an autophagy-independent manner
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Although malignant gliomas frequently show aberrant activation of the mammalian target of rapamycin (mTOR), mTOR inhibitors have performed poorly in clinical trials. Besides regulating cell growth and translation, mTOR controls the initiation of autophagy. By recycling cellular components, autophagy can mobilize energy resources, and has thus been...
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Inhibition of mTOR signaling protects human glioma cells from hypoxia-induced cell death in an autophagy-independent manner
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TN_cdi_doaj_primary_oai_doaj_org_article_b2d083bc71b34d12a417806d3a467b6b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b2d083bc71b34d12a417806d3a467b6b
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ISSN
2058-7716
E-ISSN
2058-7716
DOI
10.1038/s41420-022-01195-y
