Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration
Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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The goal of replenishing the cardiomyocyte (CM) population using regenerative therapies following myocardial infarction (MI) is hampered by the limited regeneration capacity of adult CMs, partially due to their withdrawal from the cell cycle. Here, we show that microRNA-128 (
miR-128
) is upregulated in CMs during the postnatal switch from pr...
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Full title
Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration
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TN_cdi_doaj_primary_oai_doaj_org_article_b31199b519cc42139b0e79ff4459abd5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b31199b519cc42139b0e79ff4459abd5
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03019-z