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Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration

Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b31199b519cc42139b0e79ff4459abd5

Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration

About this item

Full title

Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-02, Vol.9 (1), p.700-16, Article 700

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The goal of replenishing the cardiomyocyte (CM) population using regenerative therapies following myocardial infarction (MI) is hampered by the limited regeneration capacity of adult CMs, partially due to their withdrawal from the cell cycle. Here, we show that microRNA-128 (
miR-128
) is upregulated in CMs during the postnatal switch from pr...

Alternative Titles

Full title

Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b31199b519cc42139b0e79ff4459abd5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b31199b519cc42139b0e79ff4459abd5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-03019-z

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