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Ventral striatal islands of Calleja neurons bidirectionally mediate depression-like behaviors in mic...

Ventral striatal islands of Calleja neurons bidirectionally mediate depression-like behaviors in mic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b3431fd88a3540e0906c1897b6e26823

Ventral striatal islands of Calleja neurons bidirectionally mediate depression-like behaviors in mice

About this item

Full title

Ventral striatal islands of Calleja neurons bidirectionally mediate depression-like behaviors in mice

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-10, Vol.14 (1), p.6887-6887, Article 6887

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The ventral striatum is a reward center implicated in the pathophysiology of depression. It contains islands of Calleja, clusters of dopamine D3 receptor-expressing granule cells, predominantly in the olfactory tubercle (OT). These OT D3 neurons regulate self-grooming, a repetitive behavior manifested in affective disorders. Here we show that chron...

Alternative Titles

Full title

Ventral striatal islands of Calleja neurons bidirectionally mediate depression-like behaviors in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b3431fd88a3540e0906c1897b6e26823

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b3431fd88a3540e0906c1897b6e26823

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-42662-z

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