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Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites tha...

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites tha...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b35581fcdf054cdeaf34fbdef20d8aac

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission

About this item

Full title

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-06, Vol.7 (1), p.4342-14, Article 4342

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain. Here, we show that oxidized LA-derived metabolites accumulate in several rat brain regions during CO
2
-induced ischemia and that LA-derived 13-hydroxyoctadecadienoic acid, but...

Alternative Titles

Full title

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b35581fcdf054cdeaf34fbdef20d8aac

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b35581fcdf054cdeaf34fbdef20d8aac

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-02914-7

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