A 3D adipogenesis platform to study the fate of fibro/adipogenic progenitors in muscular dystrophies
A 3D adipogenesis platform to study the fate of fibro/adipogenic progenitors in muscular dystrophies
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Publisher
England: Cambridge Company of Biologists
Journal title
Language
English
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Publisher
England: Cambridge Company of Biologists
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Contents
In human dystrophies, progressive muscle wasting is exacerbated by ectopic deposition of fat and fibrous tissue originating from fibro/adipogenic progenitors (FAPs). In degenerating muscles, the ability of these cells to promote successful healing is attenuated, and FAPs aberrantly expand and differentiate into adipocytes and fibroblasts. Thus, arr...
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Full title
A 3D adipogenesis platform to study the fate of fibro/adipogenic progenitors in muscular dystrophies
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TN_cdi_doaj_primary_oai_doaj_org_article_b35710252e3c49fd83b1ee9eb6a58db2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b35710252e3c49fd83b1ee9eb6a58db2
Other Identifiers
ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.049915
