Sleep fragmentation exacerbates myocardial ischemia‒reperfusion injury by promoting copper overload...
Sleep fragmentation exacerbates myocardial ischemia‒reperfusion injury by promoting copper overload in cardiomyocytes
About this item
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Author / Creator
Chen, Na , Guo, Lizhe , Wang, Lu , Dai, Sisi , Zhu, Xiaocheng and Wang, E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Sleep disorders increase the risk and mortality of heart disease, but the brain-heart interaction has not yet been fully elucidated. Cuproptosis is a copper-dependent type of cell death activated by the excessive accumulation of intracellular copper. Here, we showed that 16 weeks of sleep fragmentation (SF) resulted in elevated copper levels in the...
Alternative Titles
Full title
Sleep fragmentation exacerbates myocardial ischemia‒reperfusion injury by promoting copper overload in cardiomyocytes
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b3a666f476cc4e049cec7d0639e118fe
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b3a666f476cc4e049cec7d0639e118fe
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-48227-y
