Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following...
Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Astrocytes extend endfeet that enwrap the vasculature, and disruptions to this association which may occur in disease coincide with breaches in blood-brain barrier (BBB) integrity. Here we investigate if focal ablation of astrocytes is sufficient to disrupt the BBB in mice. Targeted two-photon chemical apoptotic ablation of astrocytes induced a pla...
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Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age
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TN_cdi_doaj_primary_oai_doaj_org_article_b3b85e5732634c8688cf6cefe5d58c21
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b3b85e5732634c8688cf6cefe5d58c21
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29475-2