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Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following...

Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b3b85e5732634c8688cf6cefe5d58c21

Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age

About this item

Full title

Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-04, Vol.13 (1), p.1794-1794, Article 1794

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Astrocytes extend endfeet that enwrap the vasculature, and disruptions to this association which may occur in disease coincide with breaches in blood-brain barrier (BBB) integrity. Here we investigate if focal ablation of astrocytes is sufficient to disrupt the BBB in mice. Targeted two-photon chemical apoptotic ablation of astrocytes induced a pla...

Alternative Titles

Full title

Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b3b85e5732634c8688cf6cefe5d58c21

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b3b85e5732634c8688cf6cefe5d58c21

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-29475-2

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