Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank
Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank
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Author / Creator
Valette, Kim , Li, Zhonglin , Bon-Baret, Valentin , Chignon, Arnaud , Bérubé, Jean-Christophe , Eslami, Aida , Lamothe, Jennifer , Gaudreault, Nathalie , Joubert, Philippe , Obeidat, Ma’en , van den Berge, Maarten , Timens, Wim , Sin, Don D. , Nickle, David C. , Hao, Ke , Labbé, Catherine , Godbout, Krystelle , Côté, Andréanne , Laviolette, Michel , Boulet, Louis-Philippe , Mathieu, Patrick , Thériault, Sébastien and Bossé, Yohan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
To identify candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls). We then carried out functional mapping through transcriptome-wide association studies (TWAS) and Mendelian randomization in lung (n = 1,038) and blood (n = 31,68...
Alternative Titles
Full title
Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank
Authors, Artists and Contributors
Author / Creator
Li, Zhonglin
Bon-Baret, Valentin
Chignon, Arnaud
Bérubé, Jean-Christophe
Eslami, Aida
Lamothe, Jennifer
Gaudreault, Nathalie
Joubert, Philippe
Obeidat, Ma’en
van den Berge, Maarten
Timens, Wim
Sin, Don D.
Nickle, David C.
Hao, Ke
Labbé, Catherine
Godbout, Krystelle
Côté, Andréanne
Laviolette, Michel
Boulet, Louis-Philippe
Mathieu, Patrick
Thériault, Sébastien
Bossé, Yohan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b3d76be062194736bdde905088a0270a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b3d76be062194736bdde905088a0270a
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-02227-6
