Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mec...
Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors
About this item
Full title
Author / Creator
Knopf, Philipp , Stowbur, Dimitri , Hoffmann, Sabrina H. L. , Hermann, Natalie , Maurer, Andreas , Bucher, Valentina , Poxleitner, Marilena , Tako, Bredi , Sonanini, Dominik , Krishnamachary, Balaji , Sinharay, Sanhita , Fehrenbacher, Birgit , Gonzalez-Menendez, Irene , Reckmann, Felix , Bomze, David , Flatz, Lukas , Kramer, Daniela , Schaller, Martin , Forchhammer, Stephan , Bhujwalla, Zaver M. , Quintanilla-Martinez, Leticia , Schulze-Osthoff, Klaus , Pagel, Mark D. , Fransen, Marieke F. , Röcken, Martin , Martins, André F. , Pichler, Bernd J. , Ghoreschi, Kamran and Kneilling, Manfred
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
Subjects
More information
Scope and Contents
Contents
Immune checkpoint inhibitors have revolutionized cancer therapy, yet the efficacy of these treatments is often limited by the heterogeneous and hypoxic tumor microenvironment (TME) of solid tumors. In the TME, programmed death-ligand 1 (PD-L1) expression on cancer cells is mainly regulated by Interferon-gamma (IFN-γ), which induces T cell exhaustio...
Alternative Titles
Full title
Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors
Authors, Artists and Contributors
Author / Creator
Stowbur, Dimitri
Hoffmann, Sabrina H. L.
Hermann, Natalie
Maurer, Andreas
Bucher, Valentina
Poxleitner, Marilena
Tako, Bredi
Sonanini, Dominik
Krishnamachary, Balaji
Sinharay, Sanhita
Fehrenbacher, Birgit
Gonzalez-Menendez, Irene
Reckmann, Felix
Bomze, David
Flatz, Lukas
Kramer, Daniela
Schaller, Martin
Forchhammer, Stephan
Bhujwalla, Zaver M.
Quintanilla-Martinez, Leticia
Schulze-Osthoff, Klaus
Pagel, Mark D.
Fransen, Marieke F.
Röcken, Martin
Martins, André F.
Pichler, Bernd J.
Ghoreschi, Kamran
Kneilling, Manfred
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b3fa661fa2c8409a83b991ccda94efe7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b3fa661fa2c8409a83b991ccda94efe7
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-023-01900-0
