SHANK3 Downregulation in the Ventral Tegmental Area Accelerates the Extinction of Contextual Associa...
SHANK3 Downregulation in the Ventral Tegmental Area Accelerates the Extinction of Contextual Associations Induced by Juvenile Non-familiar Conspecific Interaction
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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Contents
Haploinsufficiency of the
gene, encoding for a scaffolding protein located in the postsynaptic density of glutamatergic synapse, has been linked to forms of autism spectrum disorders (ASDs). It has been shown that SHANK3 controls the maturation of social reward circuits in the ventral tegmental area (VTA). Whether the impairments in associative...
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Full title
SHANK3 Downregulation in the Ventral Tegmental Area Accelerates the Extinction of Contextual Associations Induced by Juvenile Non-familiar Conspecific Interaction
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TN_cdi_doaj_primary_oai_doaj_org_article_b4276b4f005246508527ae0534ad6cfc
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4276b4f005246508527ae0534ad6cfc
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2018.00360
