DNA 5-methylcytosine detection and methylation phasing using PacBio circular consensus sequencing
DNA 5-methylcytosine detection and methylation phasing using PacBio circular consensus sequencing
About this item
Full title
Author / Creator
Ni, Peng , Nie, Fan , Zhong, Zeyu , Xu, Jinrui , Huang, Neng , Zhang, Jun , Zhao, Haochen , Zou, You , Huang, Yuanfeng , Li, Jinchen , Xiao, Chuan-Le , Luo, Feng and Wang, Jianxin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Long single-molecular sequencing technologies, such as PacBio circular consensus sequencing (CCS) and nanopore sequencing, are advantageous in detecting DNA 5-methylcytosine in CpGs (5mCpGs), especially in repetitive genomic regions. However, existing methods for detecting 5mCpGs using PacBio CCS are less accurate and robust. Here, we present ccsme...
Alternative Titles
Full title
DNA 5-methylcytosine detection and methylation phasing using PacBio circular consensus sequencing
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b435a571fd5c4859becd0a26f53b6164
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b435a571fd5c4859becd0a26f53b6164
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39784-9
