Genomic programming of IRF4-expressing human Langerhans cells
Genomic programming of IRF4-expressing human Langerhans cells
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Full title
Author / Creator
Sirvent, Sofia , Vallejo, Andres F. , Davies, James , Clayton, Kalum , Wu, Zhiguo , Woo, Jeongmin , Riddell, Jeremy , Chaudhri, Virendra K. , Stumpf, Patrick , Nazlamova, Liliya Angelova , Wheway, Gabrielle , Rose-Zerilli, Matthew , West, Jonathan , Pujato, Mario , Chen, Xiaoting , Woelk, Christopher H. , MacArthur, Ben , Ardern-Jones, Michael , Friedmann, Peter S. , Weirauch, Matthew T. , Singh, Harinder and Polak, Marta E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Langerhans cells (LC) can prime tolerogenic as well as immunogenic responses in skin, but the genomic states and transcription factors (TF) regulating these context-specific responses are unclear. Bulk and single-cell transcriptional profiling demonstrates that human migratory LCs are robustly programmed for MHC-I and MHC-II antigen presentation. C...
Alternative Titles
Full title
Genomic programming of IRF4-expressing human Langerhans cells
Authors, Artists and Contributors
Author / Creator
Vallejo, Andres F.
Davies, James
Clayton, Kalum
Wu, Zhiguo
Woo, Jeongmin
Riddell, Jeremy
Chaudhri, Virendra K.
Stumpf, Patrick
Nazlamova, Liliya Angelova
Wheway, Gabrielle
Rose-Zerilli, Matthew
West, Jonathan
Pujato, Mario
Chen, Xiaoting
Woelk, Christopher H.
MacArthur, Ben
Ardern-Jones, Michael
Friedmann, Peter S.
Weirauch, Matthew T.
Singh, Harinder
Polak, Marta E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b437083920e842f086e6d17c31b3b048
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b437083920e842f086e6d17c31b3b048
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-14125-x
