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AraC Functional Suppressors of Mutations in the C-Terminal Domain of the RpoA Subunit of the Escheri...

AraC Functional Suppressors of Mutations in the C-Terminal Domain of the RpoA Subunit of the Escheri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4381c5e6ed94cbfb10d0a65a0d1e105

AraC Functional Suppressors of Mutations in the C-Terminal Domain of the RpoA Subunit of the Escherichia coli RNA Polymerase

About this item

Full title

AraC Functional Suppressors of Mutations in the C-Terminal Domain of the RpoA Subunit of the Escherichia coli RNA Polymerase

Publisher

Switzerland: MDPI AG

Journal title

Microorganisms (Basel), 2024-09, Vol.12 (9), p.1928

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

In E. coli, transcriptional activation is often mediated by the C-terminal domain of RpoA, the α subunit of RNA polymerase. Random mutations that prevent activation of the arabinose PBAD promoter are clustered in the RpoA C-terminal domain (α-CTD). We have isolated functional suppressors of rpoA α-CTD mutations that map to araC, the main transcript...

Alternative Titles

Full title

AraC Functional Suppressors of Mutations in the C-Terminal Domain of the RpoA Subunit of the Escherichia coli RNA Polymerase

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b4381c5e6ed94cbfb10d0a65a0d1e105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4381c5e6ed94cbfb10d0a65a0d1e105

Other Identifiers

ISSN

2076-2607

E-ISSN

2076-2607

DOI

10.3390/microorganisms12091928

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