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Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopath...

Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopath...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b43e86d8a3fb4c32a9cf3d2361bda63e

Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopathy

About this item

Full title

Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopathy

Publisher

Switzerland: MDPI

Journal title

Metabolites, 2020-02, Vol.10 (2), p.69

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Alzheimer’s disease (AD) is characterized, amongst other features, by the pathologic accumulation of abnormally phosphorylated tau filaments in neurons that lead to neurofibrillary tangles. However, the molecular mechanisms by which the abnormal processing of tau leads to neurodegeneration and cognitive impairment remain unknown. Metabolomic techni...

Alternative Titles

Full title

Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b43e86d8a3fb4c32a9cf3d2361bda63e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b43e86d8a3fb4c32a9cf3d2361bda63e

Other Identifiers

ISSN

2218-1989

E-ISSN

2218-1989

DOI

10.3390/metabo10020069

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