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Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO...

Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4419ac41c554af68c918ae4ee7c5d81

Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life

About this item

Full title

Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-07, Vol.13 (1), p.4352-21, Article 4352

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Obesity is a pre-disposing condition for chronic obstructive pulmonary disease, asthma, and pulmonary arterial hypertension. Accumulating evidence suggests that metabolic influences during development can determine chronic lung diseases (CLD). We demonstrate that maternal obesity causes early metabolic disorder in the offspring. Here, interleukin-6...

Alternative Titles

Full title

Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b4419ac41c554af68c918ae4ee7c5d81

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4419ac41c554af68c918ae4ee7c5d81

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-31655-z

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