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Glycolytic inhibitor 2-deoxyglucose simultaneously targets cancer and endothelial cells to suppress...

Glycolytic inhibitor 2-deoxyglucose simultaneously targets cancer and endothelial cells to suppress...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4494866852d4630a7c1d6d2d02f9e57

Glycolytic inhibitor 2-deoxyglucose simultaneously targets cancer and endothelial cells to suppress neuroblastoma growth in mice

About this item

Full title

Glycolytic inhibitor 2-deoxyglucose simultaneously targets cancer and endothelial cells to suppress neuroblastoma growth in mice

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2015-10, Vol.8 (10), p.1247-1254

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

Neuroblastoma is characterized by a wide range of clinical manifestations and associated with poor prognosis when there is amplification of MYCN oncogene or high expression of Myc oncoproteins. In a previous in vitro study, we found that the glycolytic inhibitor 2-deoxyglucose (2DG) could suppress the growth of neuroblastoma cells, particularly in...

Alternative Titles

Full title

Glycolytic inhibitor 2-deoxyglucose simultaneously targets cancer and endothelial cells to suppress neuroblastoma growth in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b4494866852d4630a7c1d6d2d02f9e57

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4494866852d4630a7c1d6d2d02f9e57

Other Identifiers

ISSN

1754-8403,1754-8411

E-ISSN

1754-8411,1754-8403

DOI

10.1242/dmm.021667

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