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Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition

Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4516b779c584d51bd450c2b733bcee2

Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition

About this item

Full title

Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition

Publisher

England: eLife Sciences Publications, Ltd

Journal title

eLife, 2015-08, Vol.4

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications, Ltd

More information

Scope and Contents

Contents

The adaptive prokaryotic immune system CRISPR-Cas provides RNA-mediated protection from invading genetic elements. The fundamental basis of the system is the ability to capture small pieces of foreign DNA for incorporation into the genome at the CRISPR locus, a process known as Adaptation, which is dependent on the Cas1 and Cas2 proteins. We demons...

Alternative Titles

Full title

Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b4516b779c584d51bd450c2b733bcee2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4516b779c584d51bd450c2b733bcee2

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.08716

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