Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition
Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition
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England: eLife Sciences Publications, Ltd
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English
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England: eLife Sciences Publications, Ltd
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The adaptive prokaryotic immune system CRISPR-Cas provides RNA-mediated protection from invading genetic elements. The fundamental basis of the system is the ability to capture small pieces of foreign DNA for incorporation into the genome at the CRISPR locus, a process known as Adaptation, which is dependent on the Cas1 and Cas2 proteins. We demons...
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Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition
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TN_cdi_doaj_primary_oai_doaj_org_article_b4516b779c584d51bd450c2b733bcee2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4516b779c584d51bd450c2b733bcee2
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.08716