Cell-to-cell transmitted alpha-synuclein recapitulates experimental Parkinson’s disease
Cell-to-cell transmitted alpha-synuclein recapitulates experimental Parkinson’s disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Parkinson’s disease is characterized by a progressive accumulation of alpha-Synuclein (αSyn) neuronal inclusions called Lewy bodies in the nervous system. Lewy bodies can arise from the cell-to-cell propagation of αSyn, which can occur via sequential steps of secretion and uptake. Here, by fusing a removable short signal peptide to the N-terminus o...
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Cell-to-cell transmitted alpha-synuclein recapitulates experimental Parkinson’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_b475e19f60dc407d997399ffc8c7268c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b475e19f60dc407d997399ffc8c7268c
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2373-8057
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2373-8057
DOI
10.1038/s41531-023-00618-6