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Cell-to-cell transmitted alpha-synuclein recapitulates experimental Parkinson’s disease

Cell-to-cell transmitted alpha-synuclein recapitulates experimental Parkinson’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b475e19f60dc407d997399ffc8c7268c

Cell-to-cell transmitted alpha-synuclein recapitulates experimental Parkinson’s disease

About this item

Full title

Cell-to-cell transmitted alpha-synuclein recapitulates experimental Parkinson’s disease

Publisher

London: Nature Publishing Group UK

Journal title

NPJ Parkinson's Disease, 2024-01, Vol.10 (1), p.10-10, Article 10

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Parkinson’s disease is characterized by a progressive accumulation of alpha-Synuclein (αSyn) neuronal inclusions called Lewy bodies in the nervous system. Lewy bodies can arise from the cell-to-cell propagation of αSyn, which can occur via sequential steps of secretion and uptake. Here, by fusing a removable short signal peptide to the N-terminus o...

Alternative Titles

Full title

Cell-to-cell transmitted alpha-synuclein recapitulates experimental Parkinson’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b475e19f60dc407d997399ffc8c7268c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b475e19f60dc407d997399ffc8c7268c

Other Identifiers

ISSN

2373-8057

E-ISSN

2373-8057

DOI

10.1038/s41531-023-00618-6

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