Polo-like kinase 1 promotes pulmonary hypertension
Polo-like kinase 1 promotes pulmonary hypertension
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Author / Creator
Chen, Rongrong , Wang, Hongfei , Zheng, Cuiting , Zhang, Xiyu , Li, Li , Wang, Shengwei , Chen, Hongyu , Duan, Jing , Zhou, Xian , Peng, Haiyong , Guo, Jing , Zhang, Anchen , Li, Feifei , Wang, Wang , Zhang, Yu , Wang, Jun , Wang, Chen , Meng, Yan , Du, Xinling and Zhang, Hongbing
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Pulmonary hypertension (PH) is a lethal vascular disease with limited therapeutic options. The mechanistic connections between alveolar hypoxia and PH are not well understood. The aim of this study was to investigate the role of mitotic regulator Polo-like kinase 1 (PLK1) in PH development.
Mouse lungs along with human pulmonary arterial smooth...
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Full title
Polo-like kinase 1 promotes pulmonary hypertension
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TN_cdi_doaj_primary_oai_doaj_org_article_b48611da284a49b3adfca50cf5e3ebbe
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b48611da284a49b3adfca50cf5e3ebbe
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ISSN
1465-993X,1465-9921
E-ISSN
1465-993X,1465-9921
DOI
10.1186/s12931-023-02498-z
