Log in to save to my catalogue

Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymph...

Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymph...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b49ae641f8704cfbb9d4caceb9a13345

Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymphoblastoid cell lines

About this item

Full title

Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymphoblastoid cell lines

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2021-01, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Lymphoblastoid cell lines (LCLs) are generated by transforming primary B cells with Epstein–Barr virus (EBV) and are used extensively as model systems in viral oncology, immunology, and human genetics research. In this study, we characterized single-cell transcriptomic profiles of five LCLs and present a simple discrete-time simulation to explore t...

Alternative Titles

Full title

Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymphoblastoid cell lines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b49ae641f8704cfbb9d4caceb9a13345

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b49ae641f8704cfbb9d4caceb9a13345

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.62586

How to access this item