Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors
Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors
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Basel: MDPI AG
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Language
English
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Basel: MDPI AG
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Heat shock protein 90 (Hsp90) is a chaperone responsible for the maturation of many cancer-related proteins, and is therefore an important target for the design of new anticancer agents. Several Hsp90 N-terminal domain inhibitors have been evaluated in clinical trials, but none have been approved as cancer therapies. This is partly due to induction...
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Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_b49f7cc271014f1080fd907cb4d11058
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b49f7cc271014f1080fd907cb4d11058
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ISSN
1999-4923
E-ISSN
1999-4923
DOI
10.3390/pharmaceutics13081283
