Mycobacterial HelD connects RNA polymerase recycling with transcription initiation
Mycobacterial HelD connects RNA polymerase recycling with transcription initiation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Mycobacterial HelD is a transcription factor that recycles stalled RNAP by dissociating it from nucleic acids and, if present, from the antibiotic rifampicin. The rescued RNAP, however, must disengage from HelD to participate in subsequent rounds of transcription. The mechanism of release is unknown. We show that HelD from
Mycobacterium smegmati...
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Full title
Mycobacterial HelD connects RNA polymerase recycling with transcription initiation
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TN_cdi_doaj_primary_oai_doaj_org_article_b4ae507a61d547bd9ec5f46e0019e458
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4ae507a61d547bd9ec5f46e0019e458
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-52891-5
