NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport
NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport
About this item
Full title
Author / Creator
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Bioenergetic maladaptations and axonopathy are often found in the early stages of neurodegeneration. Nicotinamide adenine dinucleotide (NAD), an essential cofactor for energy metabolism, is mainly synthesized by Nicotinamide mononucleotide adenylyl transferase 2 (NMNAT2) in CNS neurons. NMNAT2 mRNA levels are reduced in the brains of Alzheimer's, P...
Alternative Titles
Full title
NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b4cc4bd0d6814ca5997b7215a718255b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4cc4bd0d6814ca5997b7215a718255b
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-023-00690-9
