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Absolute quantification of cohesin, CTCF and their regulators in human cells

Absolute quantification of cohesin, CTCF and their regulators in human cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4dd695cfba54d39a1aacd86fcfa079a

Absolute quantification of cohesin, CTCF and their regulators in human cells

About this item

Full title

Absolute quantification of cohesin, CTCF and their regulators in human cells

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2019-06, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The organisation of mammalian genomes into loops and topologically associating domains (TADs) contributes to chromatin structure, gene expression and recombination. TADs and many loops are formed by cohesin and positioned by CTCF. In proliferating cells, cohesin also mediates sister chromatid cohesion, which is essential for chromosome segregation....

Alternative Titles

Full title

Absolute quantification of cohesin, CTCF and their regulators in human cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b4dd695cfba54d39a1aacd86fcfa079a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4dd695cfba54d39a1aacd86fcfa079a

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.46269

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