Absolute quantification of cohesin, CTCF and their regulators in human cells
Absolute quantification of cohesin, CTCF and their regulators in human cells
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Author / Creator
Holzmann, Johann , Politi, Antonio Z , Nagasaka, Kota , Hantsche-Grininger, Merle , Walther, Nike , Koch, Birgit , Fuchs, Johannes , Dürnberger, Gerhard , Tang, Wen , Ladurner, Rene , Stocsits, Roman R , Busslinger, Georg A , Novák, Béla , Mechtler, Karl , Davidson, Iain Finley , Ellenberg, Jan and Peters, Jan-Michael
Publisher
England: eLife Science Publications, Ltd
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English
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Publisher
England: eLife Science Publications, Ltd
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Contents
The organisation of mammalian genomes into loops and topologically associating domains (TADs) contributes to chromatin structure, gene expression and recombination. TADs and many loops are formed by cohesin and positioned by CTCF. In proliferating cells, cohesin also mediates sister chromatid cohesion, which is essential for chromosome segregation....
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Full title
Absolute quantification of cohesin, CTCF and their regulators in human cells
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TN_cdi_doaj_primary_oai_doaj_org_article_b4dd695cfba54d39a1aacd86fcfa079a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4dd695cfba54d39a1aacd86fcfa079a
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.46269