RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages
RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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ADAR1-dependent A-to-I editing has recently been recognized as a key process for marking dsRNA as self, therefore, preventing innate immune activation and affecting the development and resolution of immune-mediated diseases and infections. Here, we have determined the role of ADAR1 as a regulator of innate immune activation and modifier of viral su...
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RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages
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TN_cdi_doaj_primary_oai_doaj_org_article_b5349f651b58471ab2d3235a717d05d0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b5349f651b58471ab2d3235a717d05d0
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-13580-0