Log in to save to my catalogue

RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b5349f651b58471ab2d3235a717d05d0

RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

About this item

Full title

RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-10, Vol.7 (1), p.13339-14, Article 13339

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

ADAR1-dependent A-to-I editing has recently been recognized as a key process for marking dsRNA as self, therefore, preventing innate immune activation and affecting the development and resolution of immune-mediated diseases and infections. Here, we have determined the role of ADAR1 as a regulator of innate immune activation and modifier of viral su...

Alternative Titles

Full title

RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b5349f651b58471ab2d3235a717d05d0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b5349f651b58471ab2d3235a717d05d0

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-13580-0

How to access this item