Phosphate regulator PhoP directly and indirectly controls transcription of the erythromycin biosynth...
Phosphate regulator PhoP directly and indirectly controls transcription of the erythromycin biosynthesis genes in Saccharopolyspora erythraea
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Author / Creator
Xu, Ya , You, Di , Yao, Li-Li , Chu, Xiaohe and Ye, Bang-Ce
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The choice of phosphate/nitrogen source and their concentrations have been shown to have great influences on antibiotic production. However, the underlying mechanisms responsible for this remain poorly understood.
We show that nutrient-sensing regulator PhoP (phosphate regulator) binds to and upregulates most of genes (ery cluster genes) involve...
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Full title
Phosphate regulator PhoP directly and indirectly controls transcription of the erythromycin biosynthesis genes in Saccharopolyspora erythraea
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TN_cdi_doaj_primary_oai_doaj_org_article_b54265f546284424b3a7207fc25f79c1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b54265f546284424b3a7207fc25f79c1
Other Identifiers
ISSN
1475-2859
E-ISSN
1475-2859
DOI
10.1186/s12934-019-1258-y
