Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically...
Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically induced with osteoarthritis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
It has been suggested that mitochondrial dysfunction and mtDNA variations may contribute to osteoarthritis (OA) pathogenesis. However, the causative link to support this claim is lacking. Here, we surgically-induced OA in conplastic mice in order to evaluate the functional consequences of mtDNA haplotypes in their joint degeneration. BL/6
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Full title
Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically induced with osteoarthritis
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TN_cdi_doaj_primary_oai_doaj_org_article_b5574bd366dc4090abea5086ff794bf4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b5574bd366dc4090abea5086ff794bf4
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-88083-0
