The p63 C-terminus is essential for murine oocyte integrity
The p63 C-terminus is essential for murine oocyte integrity
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Author / Creator
Lena, Anna Maria , Rossi, Valerio , Osterburg, Susanne , Smirnov, Artem , Osterburg, Christian , Tuppi, Marcel , Cappello, Angela , Amelio, Ivano , Dötsch, Volker , De Felici, Massimo , Klinger, Francesca Gioia , Annicchiarico-Petruzzelli, Margherita , Valensise, Herbert , Melino, Gerry and Candi, Eleonora
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The transcription factor p63 mediates distinct cellular responses, primarily regulating epithelial and oocyte biology. In addition to the two amino terminal isoforms, TAp63 and ΔNp63, the 3’-end of p63 mRNA undergoes tissue-specific alternative splicing that leads to several isoforms, including p63α, p63β and p63γ. To investigate in vivo how the di...
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Full title
The p63 C-terminus is essential for murine oocyte integrity
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TN_cdi_doaj_primary_oai_doaj_org_article_b56f4fb86c8f48deb2fe8058b99c748d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b56f4fb86c8f48deb2fe8058b99c748d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20669-0
