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New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Dock...

New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Dock...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b5735c84c2094c0ebb34c939bf9bf0df

New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Docking

About this item

Full title

New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Docking

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2020-08, Vol.25 (15), p.3540

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Colchicine is a well-known anticancer compound showing antimitotic effect on cells. Its high cytotoxic activity against different cancer cell lines has been demonstrated many times. In this paper we report the syntheses and spectroscopic analyses of novel colchicine derivatives obtained by structural modifications at C7 (carbon-nitrogen single bond...

Alternative Titles

Full title

New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Docking

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b5735c84c2094c0ebb34c939bf9bf0df

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b5735c84c2094c0ebb34c939bf9bf0df

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules25153540

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