Raster plots machine learning to predict the seizure liability of drugs and to identify drugs
Raster plots machine learning to predict the seizure liability of drugs and to identify drugs
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In vitro microelectrode array (MEA) assessment using human induced pluripotent stem cell (iPSC)-derived neurons holds promise as a method of seizure and toxicity evaluation. However, there are still issues surrounding the analysis methods used to predict seizure and toxicity liability as well as drug mechanisms of action. In the present study, we d...
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Raster plots machine learning to predict the seizure liability of drugs and to identify drugs
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TN_cdi_doaj_primary_oai_doaj_org_article_b58e9a85f46e4b3caaa29acc28e1f91e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b58e9a85f46e4b3caaa29acc28e1f91e
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-05697-8
